Apolipoprotein E is a protein involved in the metabolism of fats in the body of mammals. The ApoE4 subtype is the most well known genetic risk factor for Alzheimer’s disease. It is also implicated in cardiovascular disease, stroke, Parkinson’s, Lewy body dementia, multiple sclerosis, and other aging-associated diseases. The underlying pathologic role of the APOE alleles may be understood in terms of its metabolic impact during aging, which has implications for optimizing our diet.

Julie Gregory is the founder and president of the ApoE4.Info non-profit, a grassroots organization of ApoE4 carriers working to prevent and reverse Alzheimer’s disease. Julie also serves as the Chief Health Liaison for Apollo Health and shares her expertise through ApoE4 Consulting, LLC. Julie recently teamed up with Dr. Dale Bredesen and his integrative physician wife, Aida Lasheen Bredesen, MD to share the diet and lifestyle strategies she uses in the book, The End of Alzheimer’s Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age.

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Robert Lufkin 0:02
Welcome back to the health longevity secrets show and I’m your host, Dr. Robert Lufkin, April lipoproteins he or April he is a protein involved in the metabolism of fats in the body of mammals. The A po e for subtype is the most well known genetic risk factor for Alzheimer’s disease. It is also implicated in cardiovascular disease, stroke, Parkinson’s disease, Lewy body dementia, multiple sclerosis and other aging Associated Diseases. The underlying pathologic role of the APL E alleles may be understood in terms of their metabolic impact during aging, which has implications for optimizing our diet. Julie Gregory is the founder and president of the A po e for dot info nonprofit, a grassroots organization of a po e for carriers working to prevent and reverse Alzheimer’s disease. Julie also serves as the chief health liaison for Apollo health and shares her expertise through April eat for consulting LLC. Julie recently teamed up with Dr. Dale Bredesen and his integrative physician wife, Ada machine Bredeson and D to share the diet and lifestyle strategy she uses in the book, the end of Alzheimer’s program, the first protocol to enhance cognition and reverse decline at any age. And now, please enjoy this interview with Julie Gregory. Hi, Julie, welcome to the show.

Julie Gregory 1:52
Hi, Brad, thank you so much for having me.

Robert Lufkin 1:57
As as founder of the AP for info organization, and, and as Chief Health liaison at Apollo health, you’re uniquely qualified to discuss some of the clinical applications and significance of the APL e4 allele. But But before we do that, maybe we could just take a moment and and hear a little bit about your how you came to be interested in in this fascinating area?

Julie Gregory 2:29
That’s a really great question. My interest in Alzheimer’s is very organic. So when I was about to turn 50, which was almost 10 years ago, I took part in genetic testing through 23andme. And I’ve learned that I carry two copies of a pro e4 allele, which as you know, greatly increases my risk for developing Alzheimer’s, somewhere around 50 to 90%. In fact, only 2% of the world’s population has a risk as high as mine a genetic risk as high as mine, although 25% of the world’s population carries at least one copy of April before. So learning that information, in retrospect, was a very positive thing, because I truly believe and looking back at saved my life, I wasn’t focused on my cognitive health at that time. But I should have been, because I was having more senior moments than was normal for a 50 year old. And learning I was at high genetic risk caused me to take part in cognitive testing. So I did my first round of cognitive testing. And I was stunned when I scored in the mid 30th percentile for my age group. A fully expected I knew I was having some slips, I would occasionally get lost when I was driving. I’m very familiar roads, I would have like a second or two where I didn’t know where I was. I was running into people in the town where I’d lived for 20 years, who knew me very well. And I had no idea for the bidding war. I fumbled my way through those conversations trying to get away. So I expected my cognitive testing wouldn’t be great. I thought maybe the 75th percentile, and I never got the mid 30. So I repeated cognitive testing. And I got the same score. So at that point, I realized not only was I at risk for Alzheimer’s, but the process had very likely because I turned to the Alzheimer’s Association for Information. And this was back in 2012. And right on their website, they said Alzheimer’s can’t be prevented. It’s untreatable, it’s incurable, it’s progressive, and most people are dead within 10 years of symptom onset. So as you can imagine, I was feeling nervous over Well, now I’m terrified. So I still thought This just can’t be I am only 50 years old, surely there’s something I can do. So I identified the best neurologist in my area, took a lot of courage for me to her set up a visit, to meet with him to tell him about my genetic risk and the symptoms I was having. And I asked him what I can do to prevent my symptoms from getting worse or to turn things around. And you want to know what he said. He said, Good luck with that.

Robert Lufkin 5:32
Wow.

Julie Gregory 5:33
I know. So the bright light for me at this point was 23. And be provided forums, where people who from all over the world were learning they were at high genetic risk for Alzheimer’s together. And we did. And as you can imagine, they were an enormous emotional support to me, because no one else understood that fear as much as someone who was also going through the same process. So we created a strong community, we became family. But we also turn to the science. And we began exploring the medical literature consulting experts reading every study, we could get our hands on, to figure out how we can turn things around. And over a period of time, a year or so we had collected over 100 pages of discussion in which we’re sharing scientific studies and so forth. And we recognized we were sitting on a treasure trove of a pulley for information that had never been collected before. So at that point, we decided to move our discussion to our own website, April, we forget info, where I created a nonprofit where we could continue gathering, exploring and learning. And we’re still doing that to that to to this day. But the most important part was it everything we were learning, I began to apply to my own life. Because I strongly believe that there were dietary patterns, lifestyle strategies, that there had to be something I could do to better support my brain. And that’s what I was searching for. And so I dramatically changed my diet. At that time, I was eating a low fat, high carb diet. That’s what my doctor told me to eat. That’s what the USDA pyramid told me to eat. I was having lots of, you know, whole grains every day. And it led me to become insulin resistant. So for the pioneering work of Dr. Stevens, who named Dr. Mary Newport, you know, this is back. In those early days, I was recognizing that healthy fats could help me get into ketosis, that could better fuel my brain. So I turn things around dramatically. I turned the food pyramid upside down. But I did it in a way that also supported my gut microbiome. Because we were also finding out those this strong connection between our gut health and our brain health, and I recognize that fiber and a strong healthy microbiome was also important. So I settled on a diet that was very high and non starchy vegetables from every color of the rainbow, preferably local, seasonal, organic, and lots of healthy fats. I also had an adequate amount of clean protein. And I did a lot of low Mercury wild caught seafood because I recognize the importance of DHA. I do a lot of pastured eggs because I recognize the importance of choline. I also gave up a lot of foods, I should have mentioned that I cut out all sugar. I cut out all simple carbohydrates. I cut out all grains, that was difficult. And I also put out conventional dairy because I learned it was pretty inflammatory. And putting all these dietary things together, you know, it took time, but I really began to feel the benefits. As I got into ketosis, I BIOL energetically felt so much more stable. As someone with insulin resistance I was on this up and down roller coaster with my blood glucose all day. And suddenly I had this steady supply of energy and I felt like my brain was on fire in a good way. So I also changed the way I exercise. At that point in my life. I was 20 pounds heavier than I am now, thanks to all those healthy wholesome grains. And I had been engaging in a very stressful boot camp style exercise. I live near the University of Georgia at that time, and I was competing with 20 year old college girls, and it was ridiculous. It was very stressful. So when I learned I wasn’t a pro e4 homozygote that I was fragile. Begin to exercise in a more supportive way. A calmer, more gentle way. I did daily 456 mile walk In nature, spending time in nature is very healing for me. Of course, I interspersed walking with running. I did strength training three to four times a week, but it was just much more gentle to my body. I also focused on getting quality restorative sleep. When I learned about the importance of sleep for brain health, I started meditating for the first time in my life, I began brain training, and I did something really stupid that I don’t recommend. I challenged myself to beat the score from the day before. So I do brain training every day. And if my score wasn’t as good as the day before, I stuck with it until it was and that was actually very stressful, which probably isn’t necessary. But it was a great way to stimulate my brain and get new neurons connecting and firing. I began to pay attention to toxins in my environment. I was learning the water, I drank the air I breathed on the food I was eating, obviously, but even the cosmetics and sunscreen I was putting on my skin had potential toxins, why identify the cleanest products I could find? It started taking targeted supplements. Curcumin was the first one. And when I took that it was like a fog lifted and rainbows came up. And I think that speaks to the high amount of inflammation I probably had in my brain and throughout my body. But I learned about the power of targeted supplements. I also started taking DHA and vitamin D and some other targeted supplements. I also began tracking some biomarkers, as I learned about their relevance to cognition, to tracking my blood glucose, my HB one C, my fasting insulin, my homocysteine, my vitamin D, and things weren’t good. I worked on them until they until they were about a year later, I repeated the cognitive testing. And my scores were in the mid 90th percentile for my age group. So I’m proof that yes, Alzheimer’s can be prevented. And maybe in the very early stages, we can even turn things around.

Fast forward to 2014. I read Dr. Bredesen, seminal paper reversal of cognitive decline, a novel therapeutic program. And as you can imagine, it just blew me away. Because in a small way, it was validation of the journey that I’ve been on. As you know, Dr. Bredesen used strategies very similar to those that I and members of April for that info community had been using. And he was able to reverse cognitive decline, and nine out of 10 of the case studies. So I reached out to Dr. Bredesen that same day, and I was done. When he emailed me back almost immediately, we got on the phone and spoke to one another. And he was so interested in my story. But he was also very interested in the work that I was doing what they paid for that info. And we’ve been working together in one way or another ever since basically spreading this message of hope.

Robert Lufkin 13:21
That’s that’s a beautiful story. I have to ask, how was your How was your health now today?

Julie Gregory 13:28
Right? You know what I my health is better than any other time in my adult life. And my cognition is very shocked to this day, 10 years later, when the Alzheimer’s Association told me I’d be dead. So I’m still here. I’m doing very well. That being said, I’m on the protocol for life. And I think addressing cognitive decline is a lot like peeling back the layers of an onion. So as we find one dragger, we learned enough air. And by partnering with Dr. Bredesen, he helped me find other things that I hadn’t yet begun to address. He helped me realize I had a 15 year old BZ osis infection. It’s a Lyme disease co infection. That was actually pretty acute. I’ve recently learned on dealing with mold. So the journey continues, I continue to explore all these new things. I’m responding very well to all the treatment, my cognitions holding, and my health is really good, you know, despite the fact that I’m offering new drivers, and I’m actually very grateful for being on that journey.

Robert Lufkin 14:41
Yeah, that’s such a great concept. That this is a journey. It’s not a the prevention it’s it’s really a lifelong, a lifelong journey that we all take it and it’s not a simple diet that you go on and then you go off but it’s really lifestyle change that we embrace? I mean, or are you on, you’re following all these things today, then correct

Julie Gregory 15:07
course and I will until the day that I died. But the benefits are so amazing that it’s easily self sustaining. It’s not a hardship to practice, the protocol just becomes your lifestyle, and you feel so good. There’s no reason not to practice it. And really, you know, all these additional things that I’m covering and addressing, well, we should all be optimizing our health every day and identifying and, you know, addressing all of these things that can be impacting our humans.

Robert Lufkin 15:37
Yeah, I love your comments about the inflammation and reducing the inflammation with with these prevention tools. And, and I, I loved reading about AP four, and the idea that the A po e4 allele is actually the oldest ancestral allele that for this particular lipoproteins that we have. So the the, our ancestors all had a bow before, but it was believed to be Do you know the? Yeah, go ahead, if you want to talk about it, or I can.

Julie Gregory 16:14
Well, a bully former was protective, certainly at that point, because it’s pro inflammatory. So as we came out of the trees and began stepping on dung and getting cuts in our feets, and all this, a poly for carriers were better protected. And it wasn’t until recently, actually that other eight pro e genotype ‘s began to emerge. So April employs the ancestral allele, I believe it certainly converges benefits to this date, or it will not persist it in the population. I think we’re learning that as long as you avoid insulin resistance and metabolic syndrome, a polling for can be very positive. Mm hmm.

Robert Lufkin 16:56
Yeah. And I just, I remember reading another paper about the distribution of the a bowie for alleles relative to the distribution of grain in the Fertile Crescent, and the Tigris and Euphrates, because when grain came on, it increased the the inflammation and affected us that way. But But yeah,

Julie Gregory 17:22
you know, that’s when April e two came onto the scene. So that’s a pretty strong argument for April, we for carriers to avoid grain. We have Millennials work approved that we can thrive on a non grain diet that still includes plenty of plants. And that’s essentially what I’ve returned to, I think they’re very ancestral way of eating in a very ancestral way of living.

Robert Lufkin 17:50
Yeah, yeah. And and what you’re doing as an apo e4 carrier, I think would you say, even applies to non carriers just as overall prevention for Alzheimer’s disease for for everyone?

Julie Gregory 18:04
Absolutely. Those of us at this extraordinarily high risk and benefit from this approach. Everybody can.

Robert Lufkin 18:12
Yeah, yeah, that that absolutely makes sense. Before you mentioned the testing that you had, when you first realize you were an employee for years, he mentioned one, one, company 23. And me, there are several other consumer facing ones out there like ancestry.com, and others, we’ll put in the show notes. Are there any that you recommend? Or that you recommend not using can can any, any, any testing work? If if someone’s interested in finding out their own information?

Julie Gregory 18:46
Yeah, there’s lots of different ways a lot of direct to consumer genetic testing now that can give you that information. You can also ask your physician to run the tests, you know, it’s offered by question by LabCorp. If you do that, however, you need to be aware of that that information is entered into your medical records. And you could be discriminated against getting long term care insurance. So that’s something to think about. And it may be more of a reason for consumers to directly get the information themselves and share it with their physicians as as necessary. But any physician can order to test as you know,

Robert Lufkin 19:25
and and many, I’m talking to talking to many people, when they order the test privately, they’ll often use an assumed name or D identify themselves. Although of course it doesn’t D identify the DNA snips that they have, but which but but at least as far as tracking that that removes one thing people may want to do that for confidentiality reasons. But

Julie Gregory 19:52
we should mention a lot of cardiology testing a lot of that blood testing my Boston heart And those automatically identify your a police status whether people want to or not. So a lot of people learn they’re a pony for carriers through doing advanced lipid testing. So yeah, that’s another way.

Robert Lufkin 20:14
Yeah, yeah, as we mentioned in the introduction, the APO e4 allele is not only a risk factor for Alzheimer’s disease, but also other things like Parkinson’s disease and stroke and cardiovascular disease. And many of the diseases that we’re seeing with with the sort of metabolic unhealth that we have. So, yeah, it could be tested for in a lot of different situations, but certainly, on the heart test, we see it there as well. This tell me about the APO e4 dot org, this this is a great organization. What, what sort of things do you provide for your members? Is it you know, is it political? Or do you have to have AP for to join? Do you do scientific research? What What role do you play?

Julie Gregory 21:08
So it’s a poli for that info, although I think we own a polling for that blog as well. So there’s

Robert Lufkin 21:17
that in the show notes, make sure that everybody has the correct link.

Julie Gregory 21:22
So um, so our primary focus is to learn all we can about the APR e4 allele, how it impacts health, and most importantly, how we can intervene to mitigate the pathological effects to that, and we are about to announce a new project where we’re gonna introduce a metabolomic platform where our members can continue there, no one research, but they can see on a cellular level, how their diet and lifestyle strategies are affecting their health. And by collecting this metabolomic information, we hope to create a longitudinal Open Access dataset that not only members of our community can mine to try to figure out which strategies lead us to vibrant health, but that members of the research community can mine as well.

Robert Lufkin 22:20
Wow, that’s a great, great project. You’ve probably you may be familiar with Dave Feldman’s project on citizen science, where it’s also a nonprofit. But they have an interesting thing with labs, called own my own my labs.com or.org, we’ll put it in the show notes. But basically, individuals can get their lab work done through that website through LabCorp, or quest, but they can, if they choose to make their data available to the community anonymized, of course, they get a discounted rate on their labs. And then Dave, and CO bond his coworker or colleague, periodically public that publish that into make it open source all the data so that anyone can mine it that way. But what you have with the AP for dot info community is is a wonderful resource of probably more AP for people together in one spot than than any, you know, any single research group.

Julie Gregory 23:30
Right? I should mention Dave as an apo e4 carrier. He’s a member of our community, and he’s one of our conferences. I think he’s done a podcast with us before as well. And he’s a wonderful example of a citizen scientist. And we’re kind of following the same model. So we’re offering the metabolomic testing at a very discounted rate, as long as people agree to allow their information to be shared into this data set. And we’re very excited members of our Board have just done the first round of testing. It was eye opening, and we’re excited to launch it to our entire community.

Robert Lufkin 24:12
Wow. That’s, that’s great.

Julie Gregory 24:15
We’re gonna learn a lot.

Robert Lufkin 24:18
Yeah, and one thing you consider I’m My background is in radiology. And so I involved in a lot of the medical imaging side, we’re thinking we’re talking reaching out to Dave about doing a medical version of citizen science or do it with citizen science to have the people could upload their images in anonymized form to databases like that, but you could do it with your images, your your people’s images on a po e for dot info, all their MRIs of their brains for hippocampal atrophy could be included there. Yeah, well

Julie Gregory 24:53
collect cognitive testing. We plan to collect data on the Giants. They’re using the lifestyle strap Jeez, you’re using supplements they’re taking, you know, we’re gonna collect as much data as we can correlate that against the metabolomics. And we think some interesting stuff will emerge.

Robert Lufkin 25:11
Wow. Yeah. That’s fascinating. So from so it sounds like from the rows from the results you’ve gotten personally and from the work that you’ve seen in the literature, what what are the main recommendations? Again, if you had to hit them on bullet points for for Alzheimer’s prevention that you’ve found so effective, and you you’d recommend those for all you’re all certainly the members of the AICPA? We’ve the members of the AICPA, we for dot info community, but also for anyone interested in Alzheimer’s prevention. Maybe you could just review those for us.

Julie Gregory 25:52
Yeah. So I think that having a clean diet is extraordinarily important, Properly fueling your brain avoiding insulin resistance. There’s probably multiple ways to get to that point. But I described the diet that I’m doing earlier, it’s now called the Keto Flex 12 Three diet. And this is something that Dr. Bredesen and his wife, Dr. Ron Ito, Lucien Bredesen and I put together, I helped them write the book, the end of Alzheimer’s program, where we describe the diet and lifestyle strategies in great detail. I wrote the center part of that book, which is a handbook, which is the how to for diet and lifestyle. So so the diet I described earlier is a diet that I would recommend to prevent cognitive decline. But I think we also can’t underestimate the importance of exercise, you know, daily, or aerobic exercise strength training three to four times a week of restorative sleep seven to eight hours every single night. So important to rule out sleep apnea. So many people have that and don’t recognize it. So it’s important that your oxygenation throughout the night is pretty similar to the amount of oxygen that you’re getting throughout the day. Stress is huge. We talked about many, many different ways that people can counteract the stress that they’re exposed to. We can’t stop ourselves from being exposed to stress, unfortunately, but we can change the way we react to it. So for me, learning mindfulness, learning meditation, just made a huge difference. We also think everyone should stimulate their brains, we all need to engage in lifelong learning. There’s this uniquely American thing where you retire, and you sit in a recliner and watch TV. That’s the exact opposite of what we should be doing. You know, we work our entire adult lives. And retirement is the time to focus our time and energy on things that fuel our passion. So learn a new language and travel to that country, learn a musical instrument and join a rock band, like whatever inspires you. So brain training is one thing you can do. But there’s many, many other things you can do to keep your brain stimulated. I mentioned earlier the importance of avoiding toxins. We’re now learning that tick borne illnesses and mold, both of which are things that have affected me, and they’ve affected a majority of the population. And most of us aren’t aware, in addition to breathing dirty air drinking dirty water, using chemicals that are skin that are clean. There’s an app of the Environmental Working Group at the skin deep database that I like that I check all my cosmetics and all my toiletries, my toothpaste, my sunscreen my moisturizer, to make sure I’m doing the cleanest thing that I can. And then I think taking targeted supplements is really important. And you’ll notice that the last tip that I recommend, because supplements are supplemental. And ideally, we should all be getting the nutrients we need through our diet, but our soils are depleted of nutrients, and it’s becoming more and more difficult. And so by checking your blood values, you can learn which supplements are important for you to be taking.

Robert Lufkin 29:27
Yeah, those are great concepts. And just to underscore the point about retirement too, that’s as we increase longevity, we’re quickly approaching the period that many of us will be seeing a retirement quote if you quote retire at age 65. You could be seeing a retirement age equal to or longer than the time you actually worked, you know, which is unsustainable, economically but also the idea of of you know, life is to be lived and do fun things that you’re passionate About and have a purpose rather than just, you know, as you say sitting idle, waiting to die.

Julie Gregory 30:08
And that’s the worst thing we can do. We’ve got to keep those neurons firing create neuroplasticity, so

Robert Lufkin 30:15
I mean, absolutely. Yeah. So So with with a bowie for dot info and with Apollo group, what ways are you spreading the words about Alzheimer’s disease prevention?

Julie Gregory 30:26
Right? Well, I’m still running the nonprofit now. I think you mentioned I’m working for Apollo health this or chief health liaison, I help translate Dr. Bredesen science into clinical practice. And so I’m serving as a protocol educator. I help Dr. Bredesen and his wife write the New York Times bestselling and of Alzheimer’s program, we’re going to be writing a book together, that takes a deeper dive into the whole food part. Because even though I think we devoted 100 pages of a 300, page book to diet, people need more. So I think we’re going to end up doing a cookbook together. And we also want to write a simplified version of the protocol. With the end of Alzheimer’s program, we tried to do that. But lots of people in like the 70s and 80s are reading the book. And they’re like, it’s nice, but I don’t really know what you’re saying. So we need a simplified version. And we recognize that, for instance, my mother is excited to have the book, but I don’t think that she’s read it, or she understands it. So we know we have more work to do to simplify our messaging. And I’m very passionate about spreading the word had I followed the advice that I got from the Alzheimer’s Association back in 2012. And my neurologist said probably wouldn’t be here today. And I think my story provides hope that there is a lot we can do. And we need to become actively engaged in our health as early as possible. You know, we need to weave cognitive health into our health plan so that I think even children should be tested for a police status, I would have loved to have known that my son was in April Lee for carrier, before he engaged in extreme skateboarding and had multiple concussions. I think that teenagers should be educated about how drugs and alcohol can affect their brain potentially for life. How high impact sports can affect their brains, getting injuries can affect you later on. I think there’s so much that we can do in terms of educating the public, and even the medical community. You know, the pathology behind Alzheimer’s takes a decade at least before symptoms show, and most likely, it takes several decades. That’s a long prodromal period. So we need to intervene Much, much sooner so that we can make this a rare disease.

Robert Lufkin 33:13
Yeah, absolutely. Absolutely. The and, and just to, to highlight what you said about the message, too, it’s, it’s this disease, saddling is so widespread, it affects everyone at all different, all different levels in the community and educational level. So to get the message out, it needs to be delivered, not only with you know, scientific articles heavily referenced with technical data for some people will need to read that other people will need a more simplified version. And some people will need just basically the bullet points, but they can all they can all learn from this and the message needs to be delivered to everyone. And to underscore another point you made about the Alzheimer’s Disease Association and the medical establishment today. It’s still this message has not been been it’s not reaching the number of people it should. We just interviewed on this program. I mean, as you mentioned, your papers with Dale Bredesen, randomized prospective, controlled studies showing Alzheimer’s disease symptoms can be reduced and and reversed in these patients with appropriate protocols. We also interviewed Matt Phillips is a neurologist in New Zealand. He just published a randomized prospective crossover controlled study on a ketogenic diet in six weeks showed improvement in Alzheimer’s disease symptoms yet. Today in nursing homes everywhere in the world. People with Alzheimer’s disease are fed refined carbohydrates and sugars. And we’ve known for over a decade that from Mary Newports work and others that, you know, there’s gonna be a significant effect. So there’s a lot of works this area and

Julie Gregory 35:19
by fighting an uphill battle. But that being said, you know, the medical community has an established delivery system, they have these appointments with a division that lasts about five to six minutes. And then at the end of which time you’re given a prescription. And this really is a matter of educating people, it’s about changing your diet, about changing your whole lifestyle. So it’s not something that can be done in a five to six minute visit. So we need to change our delivery system so that we can spread this information. And that’s why I’m so happy that you’re doing this summit, Rob, and that you’re helping to spread the word, and so passionate about this. And I really appreciate that you’re getting the word out there.

Robert Lufkin 36:12
Well, it’s such a such an important time in Alzheimer’s disease, because the we’re beginning to understand how effective these treatments can be. And and now it’s in addition to continuing that even more, it’s amount now matter getting the message out of what we already know, as you shown in yourself your own life. You’ve turned your own cognitive impairment around it’s it’s really remarkable. And it’s inspiring to hear hear your story. Julie, what advice would you give to others that are concerned about cognitive impairment or preventing Alzheimer’s disease, whether or not they have the A po e4 allele, or maybe they haven’t been tested for it?

Julie Gregory 36:59
You know what I would tell them not to believe mainstream medicine, because your local physician and your local neurologists may tell you what can’t be prevented, and there’s nothing you can do. But nothing could be farther from the truth. So take your health into your own hands. We’ve created a blueprint for you. The end of Alzheimer’s program, the programs offered by Apollo health, the information you’re sharing today, we’re helping to spread the word to get the word out there. So I think people should adapted brain healthy lifestyle as early as possible.

Robert Lufkin 37:36
Just and just one one question. I wonder. It all I always wonder if this information becomes more available with scientific studies. Why why do you think mainstream medicine isn’t more accepting of this? Why Why aren’t they serving ketogenic diets in nursing homes and, you know, doing simple things? Why is it medicine all over this? Why the why the pushback, why the resistance? Any any insights on that?

Julie Gregory 38:10
I think there’s some territorialism. I think there’s a lot of big pharma corporations that are very focused on developing the drug. And that if you acknowledged other areas of academia are having some success that takes away from your possible success. I would encourage all researchers, Big Pharma, including mainstream medicine, to forget about the territorial ism and please put the patient first, we know enough that we should be spreading this message far and wide. And believe me, a big pharma comes up with a drug. I’ll be the first to take it if it if it works, but I probably would continue the diet and lifestyle because I just feel so good doing it. We know it’s a multifactorial disease, we know there’s many, many different drivers. So it’s very unlikely, better mono therapeutic, a single drug is ever gonna have a tremendous amount of benefit. So I wish everyone could work together and just put the patient first. Unfortunately, that isn’t happening now.

Robert Lufkin 39:24
Yeah, and while as you say there is no drug that reverses the symptoms, the Alzheimer’s disease, but the best we can do is slow the rate in which it progresses, at least according to the FDA, but there are still drugs being sold and like one one cynical viewpoint about Alzheimer’s disease that I’ve heard is that it’s more profitable to give a person I’m sorry, a cynical viewpoint about diabetes. I’ve heard it’s more profitable to give a type two diabetic a prescription for insulin than it is To instruct them to avoid carbohydrates and remove the need for extra insulin as the drug and but like you’re saying there there’s territorial ism there’s competing interests and it’s it’s a complex system but but it’s a system that needs to change and hopefully by doing things like this and other things we can get the message message out there how how can people reach you Julie on social media or follow you we’re going to put everything in the show notes but for some of our audience will be listening to this in audio form could you just tell us the websites are the ways to reach you?

Julie Gregory 40:38
So please, if you’re an APL e4 carrier, or ease it, even if you’re not if you’re concerned about cognitive decline? Consider joining our community at a poli for dot info. We partnered with a functional medicine Coaching Academy and we’ve got interns read each new member and help walk them through the community and show them our resources. When I was a newly identified a poli for carrier and terrified there was a complete lack of information. And so I’m so proud that we’ve created this resource so no April Lee for carrier, or anyone concerned about Alzheimer’s disease has to feel alone, so please reach out a parolee for that info whether you’re an Aprilia for carrier or not. I’m also pretty active on Dr. Bredesen his Facebook page, we do a weekly or every two week Facebook Live. So please join us there. Consider joining the Apollo health community. They offer two programs, one for prevention and one for reversal. And I’m also very active there and I helped run a forum there as well. So please, whatever method works for you, whether it’s reading a book, joining a community, you know, using a program like Apollo Health offers, whatever it takes just begin working on your cognitive health now, I can promise your older self will thank you.

Robert Lufkin 42:06
Thank you so much, Julie. It’s been it’s been wonderful to spend an hour with you today and get to know you better and and thanks again for being on this program and for for all the great work you’re doing.

Julie Gregory 42:21
Thank you so much Brown, take care.

Unknown Speaker 42:24
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